Beker van België
FC Ganshoren – K.SK. Heist 2-2 (8-7 na penalties)
Competitie
| 11/09/2021 | 20:00 | K.SK Heist | FC.V.Dender E.H. | 2-0 |
| 19/09/2021 | 15:00 | K.Rupel Boom FC. | K.SK Heist | 0-0 |
| 25/09/2021 | 20:00 | K.SK Heist | R. Olympic Club Charleroi | 1-1 |
| 2/10/2021 | 19:30 | K.FC.Dessel Sport | K.SK Heist | 4-3 |
| 10/10/2021 | 15:00 | Francs Borains A | K.SK Heist | 0-0 |
| 16/10/2021 | 20:00 | K.SK Heist | URSL Visé A | |
| 24/10/2021 | 15:00 | R.FC.de Liège A | K.SK Heist | |
| 30/10/2021 | 20:00 | K.SK Heist | FC MU Izegem-Ingelmunster A | |
| 6/11/2021 | 19:30 | VV.Thes Sport Tessenderlo A | K.SK Heist | |
| 13/11/2021 | 20:00 | K.SK Heist | K.Patro Eisden Maasmech. A | |
| 20/11/2021 | 20:00 | La Louvière Centre A | K.SK Heist | |
| 27/11/2021 | 20:00 | K.SK Heist | K.VK.Tienen A | |
| 11/12/2021 | 20:00 | K.SK Heist | K.Sint-Eloois-Winkel Sp. A | |
| 19/12/2021 | 15:00 | R.Knokke FC. A | K.SK Heist | |
| 8/01/2022 | 20:00 | K.SK Heist | R.FC.de Liège A | |
| 15/01/2022 | 20:00 | R. Olympic Club Charleroi | K.SK Heist | |
| 22/01/2022 | 20:00 | FC MU Izegem-Ingelmunster A | K.SK Heist | |
| 29/01/2022 | 20:00 | K.SK Heist | K.Rupel Boom FC. | |
| 5/02/2022 | 20:00 | FC.V.Dender E.H. | K.SK Heist | |
| 19/02/2022 | 20:00 | K.Patro Eisden Maasmech. A | K.SK Heist | |
| 5/03/2022 | 20:00 | K.SK Heist | K.FC.Dessel Sport | |
| 13/03/2022 | 15:00 | K.Sint-Eloois-Winkel Sp. A | K.SK Heist | |
| 19/03/2022 | 20:00 | K.SK Heist | La Louvière Centre A | |
| 26/03/2022 | 20:00 | K.SK Heist | Francs Borains A | |
| 3/04/2022 | 15:00 | K.VK.Tienen A | K.SK Heist | |
| 9/04/2022 | 20:00 | K.SK Heist | VV.Thes Sport Tessenderlo A | |
| 23/04/2022 | 20:00 | URSL Visé A | K.SK Heist | |
| 30/04/2022 | 20:00 | K.SK Heist | R.Knokke FC. A |